বুধবার, ৬ ফেব্রুয়ারি, ২০১৩

Conn. congressman sees factual flaw in 'Lincoln'

HARTFORD, Conn. (AP) ? As Rep. Joe Courtney watched the Oscar-nominated "Lincoln" over the weekend, something didn't seem right to him.

He said Tuesday he was shocked that the film, about President Abraham Lincoln's political struggle to abolish slavery, includes a scene in which two Connecticut congressmen vote against the 13th amendment to the Constitution, outlawing slavery.

"'Wow. Connecticut voted against abolishing slavery?'" Courtney recalled hearing audience members ask. "I obviously had the same reaction. It was really bugging me."

He said a cursory Internet search confirmed his suspicions that the movie, directed by Steven Spielberg, was historically inaccurate. He asked the Congressional Research Service to investigate, and it reported that all four Connecticut congressmen backed the amendment in a January 1865 vote.

A spokesman for Dreamworks Pictures, which produced "Lincoln," did not immediately respond to an email seeking comment Tuesday.

Courtney praised the film's acting and cinematography but said artistic license does not permit it to inaccurately put Connecticut on the wrong side of history, particularly on an issue as powerful as slavery. In a letter to Spielberg, the four-term Democratic congressman includes a tally of the 1865 vote by the state's congressional delegation and a passionate defense of the state's role in emancipating millions of blacks.

"How could congressmen from Connecticut ? a state that supported President Lincoln and lost thousands of her sons fighting against slavery on the Union side of the Civil War ? have been on the wrong side of history?" he said in his letter.

Courtney, who majored in history at Tufts University, asked that the movie, which stars Daniel Day-Lewis as Lincoln, be corrected before its release on DVD.

"Lincoln," which leads the Oscars with 12 nominations, also stars Sally Field as Mary Todd Lincoln and Tommy Lee Jones as Thaddeus Stevens. It has earned more than $170 million at the box office.

Source: http://news.yahoo.com/conn-congressman-sees-factual-flaw-lincoln-003437629.html

2014 Corvette Stacie Halas justin timberlake Corvette Stingray Claire Danes quentin tarantino jessica chastain

Fighting fat with fat: Stem cell discovery identifies potential obesity treatment

Fighting fat with fat: Stem cell discovery identifies potential obesity treatment

Wednesday, February 6, 2013

Ottawa scientists have discovered a trigger that turns muscle stem cells into brown fat, a form of good fat that could play a critical role in the fight against obesity. The findings from Dr. Michael Rudnicki's lab, based at the Ottawa Hospital Research Institute, were published today in the prestigious journal Cell Metabolism.

"This discovery significantly advances our ability to harness this good fat in the battle against bad fat and all the associated health risks that come with being overweight and obese," says Dr. Rudnicki, a senior scientist and director for the Regenerative Medicine Program and Sprott Centre for Stem Cell Research at the Ottawa Hospital Research Institute. He is also a Canada Research Chair in Molecular Genetics and professor in the Faculty of Medicine at the University of Ottawa.

Globally, obesity is the fifth leading risk for death, with an estimated 2.8 million people dying every year from the effects of being overweight or obese, according to the World Health Organization. The Public Health Agency of Canada estimates that 25% of Canadian adults are obese.

In 2007, Dr. Rudnicki led a team that was the first to prove the existence of adult skeletal muscle stem cells. In the paper published today, Dr. Rudnicki now shows (again for the first time) that these adult muscle stem cells not only have the ability to produce muscle fibres, but also to become brown fat. Brown fat is an energy-burning tissue that is important to the body's ability to keep warm and regulate temperature. In addition, more brown fat is associated with less obesity.

Perhaps more importantly, the paper identifies how adult muscle stem cells become brown fat. The key is a small gene regulator called microRNA-133, or miR-133. When miR-133 is present, the stem cells turn into muscle fibre; when reduced, the stem cells become brown fat.

Dr. Rudnicki's lab showed that adult mice injected with an agent to reduce miR-133, called an antisense oligonucleotide or ASO, produced more brown fat, were protected from obesity and had an improved ability to process glucose. In addition, the local injection into the hind leg muscle led to increased energy production throughout the body?an effect observed after four months.

Using an ASO to treat disease by reducing the levels of specific microRNAs is a method that is already in human clinical trials. However, a potential treatment using miR-133 to combat obesity is still years away.

"While we are very excited by this breakthrough, we acknowledge that it's a first step," says Dr. Rudnicki. "There are still many questions to be answered, such as: Will it help adults who are already obese to lose weight? How should it be administered? How long do the effects last? Are there adverse effects we have not observed yet?"

###

Ottawa Hospital Research Institute: http://www.ohri.ca

Thanks to Ottawa Hospital Research Institute for this article.

This press release was posted to serve as a topic for discussion. Please comment below. We try our best to only post press releases that are associated with peer reviewed scientific literature. Critical discussions of the research are appreciated. If you need help finding a link to the original article, please contact us on twitter or via e-mail.

This press release has been viewed 42 time(s).

Source: http://www.labspaces.net/126654/Fighting_fat_with_fat__Stem_cell_discovery_identifies_potential_obesity_treatment

Pretty Little Liars Rob Parker Comcast Pokemon X and Y Rob Ryan Silver Linings Playbook david bowie

Aboard Gordon Phillips - Netrent Property Specialists

Netrent Commercial is proud to have join a new member of the Sales & Leasing team ? Gordon Phillips.

As a former President of the REIQ, Gordon?s history is all about property.
Gordon knows commercial property backwards having been a fierce agent at CBRE working up from Industrial Leasing to top where he looked after projects and major investments. Gordon then joined the Knight Frank ranks achieving an 80% success rate and selling some $400m a year under hammer.
Anyone who has been around commercial property for the last 30 years, will know of his abilities.

Gordon will command the North side of Brisbane including the Trade Coast area, and Licensed Auctioneer for Netrent Commercial ? contact him and read more about him on the Sales & Leasing Team page.

Source: http://netrent.com.au/2013/02/netrent-commercial-announcement-welcome-aboard-gordon-phillips/

matt bomer westminster kennel club dog show jeremy lin game winner chocolate covered strawberries shrimp scampi kate upton si cover lobster recipes

মঙ্গলবার, ৫ ফেব্রুয়ারি, ২০১৩

Brothers Face-off in Super Bowl in New Orleans (Voice Of America)

Share With Friends: Share on FacebookTweet ThisPost to Google-BuzzSend on GmailPost to Linked-InSubscribe to This Feed | Rss To Twitter | Politics - Top Stories News, RSS Feeds and Widgets via Feedzilla.

Source: http://news.feedzilla.com/en_us/stories/politics/top-stories/282408230?client_source=feed&format=rss

msnbc meteor shower 121212 Concert Columbine shooting News Ryan Lanza Facebook usa today

Vietnam hands down long jail terms in subversion case: TV

BANGKOK (Reuters) - A court in Vietnam has sentenced a man to life in prison and given jail terms of up to 17 years to other defendants after they were found guilty of subversive activities, state-run Vietnam Television said on Monday.

The verdict follows a series of harsh punishments handed down for dissent in the communist-ruled country, at a time of reported political infighting among the leadership centered on how to reform the economy and tackle management problems at big state firms that have led to piles of bad debt.

The People's Court of Phu Yen province gave a life sentence to Phan Van Thu, head of a group that wanted to establish a new government in Vietnam, the television station said in a news bulletin.

Jail terms of between 12 and 17 years were handed to others in the case, the television station said without elaborating.

"Their action has seriously violated the laws," it said.

People's Police newspaper, which is run by the Public Security Ministry, said Thu and others had built up their forces in a tourist resort in the central province of Phu Yen from 2004, printing a number of anti-government documents until they were arrested in February 2012.

Thu had spent time in prison for anti-government activities in the late 1970s, the newspaper said.

In January, 13 political activists were found guilty of anti-state crimes and sentenced to prison, a ruling condemned by rights activists as part of a crackdown on dissidents.

Late last month, police arrested human rights lawyer Le Quoc Quan in Hanoi after he wrote an article criticizing the Communist Party, Human Rights Watch said in its World Report 2013 published on Friday.

"The Vietnamese government is systematically suppressing freedom of expression, association, and peaceful assembly, and persecuting those who question government policies, expose official corruption, or call for democratic alternatives to one-party rule," the rights group said in its report.

The government has made no comment on the report.

Among other cases, on January 24 security forces detained a blogger in the northern province of Hung Yen and took him to a mental institution, according to a letter to Vietnam's leaders from the Paris-based Vietnam Committee on Human Rights.

Last week, the authorities deported Nguyen Quoc Quan, a U.S. national of Vietnamese origin, after keeping him in prison without trial since April last year.

Quan was accused of subversion and of being a member of Viet Tan, an outlawed pro-democracy group based in the United States, Communist Party newspaper Nhan Dan said.

Quan's trial, scheduled for January 22, was dropped and he was freed on January 30, the Viet Tan group said.

(Writing by Alan Raybould; Editing by Robert Birsel)

Source: http://news.yahoo.com/vietnam-hands-down-long-jail-terms-subversion-case-065033950.html

steve appleton bishop eddie long madonna give me all your luvin video roseanne barr president green party day 26 new hunger games trailer

DNA verdict on skeleton: It's King Richard III

The bones of King Richard III have been found in England. NBC's Stephanie Gosk reports.

By Alan Boyle, Science Editor, NBC News

Experts say DNA analysis supports their claim that the bones dug up last year under a parking lot in the English city of Leicester are the last mortal remains of England's King Richard III.

"It's the academic conclusion of the University of Leicester that beyond reasonable doubt the individual exhumed at Greyfriars in September 2012 is indeed Richard III, the last Plantagenet king of England," Richard Buckley, the project's lead archaeologist, said during a Monday news briefing in Leicester.

The project used 21st-century forensic science to solve a 500-year-old mystery surrounding one of William Shakespeare's best-known villains. Shakespeare's play, "Richard III," made the king out to be a scheming monster who killed children to get to the English throne. The bard gave Richard III dramatic lines that are still evoked today, ranging from "the winter of our discontent" to "A horse! A horse! My kingdom for a horse!"


In real life, Richard III's battlefield death in 1485 marked the end of England's Wars of the Roses, a decades-long conflict between the houses of York and Lancaster. Tradition held that he was buried in the choir of Leicester's Greyfriars Church, but the precise location of his remains was lost in the mists of time. Some even speculated that Richard's bones were thrown into the River Soar during Henry VIII's reign.

It was only in the past few years that archaeologists have been able to zero in on the location of the Greyfriars site again. Last year, a team led by the University of Leicester excavated a city parking lot and found a wealth of intriguing evidence ? including a skeleton with a battle-scarred skull?and?a spine that was curved due to scoliosis. There was no evidence of a coffin, a shroud or clothing that was buried with the body.

All those clues suggested that the skeleton could have been that of the historical Richard III, but to firm up the connection, scientists put the bones through genetic tests, radiocarbon dating and more detailed osteological analysis.

"The skull was in good condition, although fragile, and was able to give us detailed information about this individual," University of Leicester archaeologist Jo Appleby reported Sunday in a news release. During Monday's news briefing, Appleby said experts identified 10 injuries to the bones, including eight wounds to the skull and "postmortem humiliation injuries." Such wounds are "highly consistent" with the accounts of Richard III's death, she said.

"Historical sources tell us that Richard's body was stripped," hacked and put on public display after the battle, Appleby noted.

The skeleton's relatively delicate structure was consistent with descriptions of Richard III's physical appearance, University of Leicester historian Lin Foxhall said.?

University of Leicester

A photo shows the Greyfriars skeleton lying in the site where it was found.

University of Leicester

The Greyfriars skeleton is laid out for forensic analysis. Experts believe the foot bones were separated from the rest of the body after burial.

University of Leicester

The Greyfriars skull was found by researchers during a search for the remains of King Richard III.

Researchers say they've found the skeleton of King Richard III of England.

Buckley told journalists that the position of the hands suggested that they might have been bound together. Initially, the team reported that an arrowhead was found among the bones, but Buckley said a closer look determined that the object was a nail that was apparently mixed in with the remains.

Radiocarbon dating showed that "the individual could have died in 1485," Buckley said. Two tests yielded dates possibly ranging from 1455 to 1540. ?

The team's genetic analysis reinforced the link to Richard III: DNA was extracted from bone samples and compared with modern-day mitochondrial DNA from two direct descendants of Richard III's family, including an anonymous donor as well as Michael Ibsen, a Canadian-born cabinetmaker who is a 17th-generation descendant of Richard III's eldest sister, Anne of York.

"The DNA evidence points to these being the remains of Richard III," said Turi King, a geneticist at the University of Leicester. She said additional?DNA tests were still in progress.

Genetic matches based on mitochondrial DNA aren't as clear-cut as, say, a paternity test ? but a mismatch would have ruled out any family connection. Similar techniques were used to identify the remains of Czar Nicholas II and other members of Russia's royal family, who were killed in 1918 during the Russian Revolution.

A documentary about the Leicester project, "Richard III: The King in the Car Park," is to be aired by Britain's Channel 4 on Monday night. But this isn't the end of the story. For one thing, the results announced on Monday will have to go through review and publication in scientific journals. The announcement also could lead to a reassessment of Richard III's reign, which some historians say wasn't nearly as terrible as Shakespeare made it out to be.

"I think this could be the moment where Richard III's reputation actually turns," British historian Andrew Roberts told NBC News. "This could be the moment where we look at his achievements and the positive aspects of Richard III, and then just see him as one of the old Dark Ages kings."

And then there's the matter of reburying the remains: Authorities said?the skeleton would get a proper interment in Leicester Cathedral,?not far from the parking lot where it was found. The cathedral's canon chancellor, David Monteith, said planning for an interment ceremony in 2014 has already begun, and he expressed the hope that after more than 500 years, Richard III "may come to rest in peace, and rise in glory."

More about the search for Richard III:


Alan Boyle is NBCNews.com's science editor. Connect with the Cosmic Log community by "liking" the log's?Facebook page, following?@b0yle on Twitter?and adding the?Cosmic Log page?to your Google+ presence. To keep up with Cosmic Log as well as NBCNews.com's other stories about science and space, sign up for the Tech & Science newsletter, delivered to your email in-box every weekday. You can also check out?"The Case for Pluto,"?my book about the controversial dwarf planet and the search for new worlds.

Source: http://cosmiclog.nbcnews.com/_news/2013/02/04/16832540-british-experts-issue-dna-verdict-on-exhumed-skeleton-its-richard-iii?lite

zimmerman charged bonobos charles manson al sharpton actuary elon musk fox mole

রবিবার, ৩ ফেব্রুয়ারি, ২০১৩

Is your HDTV Super Bowl-ready? Set-up tips for the best view

Surveys show that about 20 percent of HDTV owners don't watch the big game and other programs in true high definition due to improper setup. Our step-by-step checklist will help you ensure that your HDTV is ready for Super Bowl viewing with the best, sharpest picture.

Ensuring your HDTV source
There are three possible ways to see the game in high definition: via cable, via satellite or over the air with an antenna.

For cable or satellite, you need to make sure you have the right equipment and settings to see the game in glorious high definition. First, make 100 percent sure your cable or satellite box is a high-definition model. If you don't specify an HD model, sometimes cable and satellite providers will rent you a standard def box. Most HD boxes have either the letters ?HD? or the words ?high definition? on their front panel. If it doesn?t, it's probably a standard def model and you'll need to get a replacement before the game.

You also need a high-definition wire to connect between the box and your HDTV. The best and least expensive one is called HDMI. It carries both the picture and sound over a single cable. Most installs need at least a two meter (6 ft.6 inches) or three meter (9 ft. 9 inches) cable. HDMI cables do not tolerate sharp bends well, so make sure the cable is long enough. Retail stores usually charge $25 to over $100 for an HDMI cable, but there are cheaper ones if you look. Amazon and other online retailers also sell them for under $10, and often with free shipping.

Cable and satellite companies still simulcast the standard definition and high definition versions of the same programming on different channels, so be sure to confirm that you are getting the HD signal. Once you've tuned in to the CBS HD channel and confirmed reception, make sure to set the box?s resolution to your HDTV's resolution. If you have a 1080p HDTV, set the box?s output to 1080i (in this case, the TV automatically converts the ?i,? for interlaced, into ?p,? for progressive ? don't worry about the definitions). If you have a 720p HDTV, set the box?s output to 720p.

You should also make sure the set top box's aspect ratio is set to 16x9 mode, and not 4x3. If this is not set correctly you will see a smaller, cropped image.

As for receiving the game over the air, you will need an antenna and you'll also have to find out if your local CBS station?s transmitter is within roughly 25 miles from your home. The good news is, there HDTV over-the-air tuner is built-in to all HDTVs. The bad news is, you need to have a line of sight to the transmitter tower. If there's a building, hill or mountain between you and the tower, you probably won?t be able to get reliable over the air reception. Check with antennaweb.org for more information about what size and type of antenna you need, as well as the direction you need to point it for each network. Because of all that is involved, the vast majority of viewers choose cable or satellite instead.

Adjusting the TV
First confirm the HDMI cable is connected from the set top box to an HDMI input on your TV. This should be the only connection between your cable box and your TV. Once you've selected that input and can see the cable programming in (hopefully) glorious high definition, it's time to open your TV's settings.

Your HDTV will have settings for aspect ratio, generally with a setting labeled Full. Select that. If your set has a sub-control called Dot-by-Dot, Native or Just Scan, then select one of those. (Panasonic TVs have a sub-menu that lists Size One or Size Two. Choose Size Two.) All these modes allow the HDTV to place the entire image on the screen without cropping it. This control gives the viewer everything the director sees at the highest resolution. Your HDTV will now match the broadcast HD signal pixel for pixel. On some HDTVs, this control may be grayed out if the set?s picture mode is set to Vivid or Sports ? you'll have to change it to Standard, Movie or Custom.

Yes, I did just say you should not use the Sports preset picture mode to watch the Super Bowl, and you should also avoid anything that says Game, or Vivid or Dynamic. It sounds counter intuitive, but these presets are generally made to produce the brightest image on the showroom floor, not the best picture in a home. Use modes such as Movie or Custom as the best starting point for user control optimization. If your set does not have those modes, simply choose Standard.

Many LED and LCD TVs that have 120Hz, 240Hz or 480Hz refresh allow users to reduce blurry motion by engaging these circuits during sports programs. Different set makers call them different names such as Motion Plus or Motion Flow, etc. This mode must be in the ?On? position to get crisper motion. Consult your TV's menu for this control, or look at the owner?s manual. Plasma TVs have full motion resolution without these circuits, so no motion adjustment is necessary on a plasma.

If you want to maximize your settings before the game, make sure you follow our guide to settings here. Ideally, you would even use a test disc like the Disney WOW: World of Wonder on Blu-ray disc to optimize your picture settings. Since you may not have time to grab that before the game, try out the new THX app for iOS devices here. It's free.

By spending a few minutes going over this super-simple list, you can be assured that you, your friends and your family are viewing the Super Bowl and all other future programs with the best high-def image your HDTV is capable of producing. Now you?ll really be ready for some football.

Have a question for the HD Guru? Send an email.

More from HD Guru:

Source: http://www.nbcnews.com/technology/gadgetbox/your-hdtv-super-bowl-ready-set-tips-best-picture-1B8189705

soylent green phil davis george st pierre aldon smith friday night lights nick santino bruce arians